
Alexis Arquette (July 28, 1969 – September 11, 2016) was an American actress and transgender activist.
Born in Los Angeles, she was the fourth of five children to Lewis Arquette, an actor and director, and Brenda Olivia "Mardi" (née Nowak), an actress. Coming from a family deeply entrenched in the entertainment industry, Alexis was the sibling of actors Rosanna, Richmond, Patricia, and David Arquette. Her career began in her youth, appearing aged 12 in the music video "She's a Beauty" by The Tubes and making her screen debut in Down and Out in Beverly Hills (1986). Known for her versatility, Arquette often performed as a female impersonator under the name "Eva Destruction", before publicly sharing her transition process towards gender-affirming surgery. Her filmography includes a range of roles, from starring roles in small productions like Jumpin' at the Boneyard (1992), Things I Never Told You (1996) and I Think I Do (1997) to appearances in mainstream hits like Threesome, Pulp Fiction (both 1994), The Wedding Singer, Bride of Chucky (both 1998), She's All That (1999) and Blended (2014).
Arquette's personal life was marked by her vocal support for the transgender community and candidness about her own transition journey, which was documented in the film Alexis Arquette: She's My Brother. Despite facing health challenges, including contracting HIV in 1987 and later health complications, Arquette continued to be an active figure in entertainment and advocacy, until her death in 2016 aged 47.
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Pulp Fiction
1994 · as Fourth Man

Blended
2014 · as Georgina

Bride of Chucky
1998 · as Damien

She's All That
1999 · as Mitch

Lords of Dogtown
2005 · as Tranny

The Wedding Singer
1998 · as George

Buffy the Vampire Slayer
1992 · as Vampire DJ (uncredited)

Of Mice and Men
1992 · as Whitt

Threesome
1994 · as Dick

Frank & Jesse
1994 · as Charlie Ford

Miracle Beach
1992 · as Lars

Spun
2003 · as Moustache Cop

Children of the Corn V: Fields of Terror
1998 · as Greg

Last Exit to Brooklyn
1989 · as Georgette

I Think I Do
1997 · as Bob

The Movie Hero
2003 · as Strange, Yet Attractive Woman

Hard Breakers
2011 · as Ms Independence

Out in Fifty
1999 · as Kim