
Fischer grew up on his father's farm Ornatsöd near Untergriesbach in the Bavarian Forest. Ottfried Fischer attended the Maristengymnasium in Fürstenzell near Passau until he graduated from high school. His father originally wanted him to become a lawyer. However, he dropped out of law school after just a few semesters.
In 1983, cabaret artist Werner Schneyder invited him to appear on his television show Meine Gäste und ich. He made his first solo appearance as a cabaret artist in 1989 with the program Schwer ist leicht was. Five years later, he made guest appearances in several German and Austrian cities with his second solo Was tun.
In between, he worked as an actor in numerous television plays, films and television series. Franz Xaver Bogner gave him his first television role in his series Zeit genug. In 1985, Bogner gave him the leading role in the series Irgendwie und Sowieso and the role of Felix in Zur Freiheit - the starting signal for a career beyond the borders of Bavaria. Fischer appeared on Bavarian radio in Der Schwammerlkönig. This was followed by feature film roles in Zärtliche Chaoten (1987), Ein Prachtexemplar (1989), Café Europa (1990), Go Trabi Go (1990), Das schreckliche Mädchen (1990) and Superstau (1991), among others.

Asterix Conquers America
1994 · as Obelix (voice)

Café Europa
1990 · as 2.Detektiv

Die blaue Kanone
1999 · as Hans Kleiber

König Otto
2006 · as Hausmeister Otto Huber

Ein Prachtexemplar
1989 · as Dr. Malzer

Langer Samstag
1992 · as Markus

Trans Bavaria
2012 · as Christian Berghammer

Ballermann 6
1997 · as Tourist

Shark Attack in the Mediterranean
2004 · as Millionär

African Race
2008 · as Baudezernent

Three Crazy Jerks
1987 · as Cook

The Nasty Girl
1990 · as Priest

Echt tu matsch
1984 · as Unertl

Holy Spirit
2019 · as Buddha

Starke Zeiten
1988 · as Willie

Qualtingers Wien
1997 · as Ehemann

Hanna Hellmann - Der Ruf der Berge
2015 · as Antonio Gimaldino

Die Superbullen
1997 · as Hans Kleiber